Book Review: Autoimmunization and the Autoimmune Hemolytic Anemias
نویسندگان
چکیده
منابع مشابه
Treatment of autoimmune hemolytic anemias.
Autoimmune hemolytic anemia (AIHA) is a relatively uncommon disorder caused by autoantibodies directed against self red blood cells. It can be idiopathic or secondary, and classified as warm, cold (cold hemagglutinin disease (CAD) and paroxysmal cold hemoglobinuria) or mixed, according to the thermal range of the autoantibody. AIHA may develop gradually, or have a fulminant onset with life-thre...
متن کاملAutoimmune hemolytic anemias and paroxysmal nocturnal hemoglobinuria
The hallmark of the autoimmune hemolytic anemias (AIHAs) and paroxysmal nocturnal hemoglobinuria (PNH) is shortened red blood cell survival. Although AIHA and PNH share the critical feature of shortened red cell survival, the mechanisms underlying this characteristic differ significantly between the two diseases. In the case of AIHA, autoantibodies directed against the patient’s own red blood c...
متن کاملHow I treat autoimmune hemolytic anemias in adults.
Autoimmune hemolytic anemia is a heterogeneous disease with respect to the type of the antibody involved and the absence or presence of an underlying condition. Treatment decisions should be based on careful diagnostic evaluation. Primary warm antibody autoimmune hemolytic anemias respond well to steroids, but most patients remain steroid-dependent, and many require second-line treatment. Curre...
متن کاملPulmonary hypertension in hemolytic anemias
Pulmonary hypertension (PH) has been reported with nearly all forms of the inherited as well as the acquired hemolytic anemias. Recent research investigating the pathophysiology of PH in sickle cell disease and thalassemia has helped elucidate the central role of hemolysis-mediated endothelial dysfunction in the development of PH in these populations. Although the most appropriate treatment of ...
متن کاملSerology of Acquired Hemolytic Anemias.
I F A SERUM contains a gamma globulin which will react with ( agglutinate, hemolyze or sens tize ) certain enetically well-defined red blood cells but not others, it is said to possess an antibody and the antibody is said to be specific for a certain property of the red cells. Thus the specificity of an antibody depends on this selective reactivity. This is often difficult to demonstrate if the...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the Royal Society of Medicine
سال: 1970
ISSN: 0035-9157
DOI: 10.1177/003591577006300442